Research based on mice has revealed that Aging and Longevity is Tied
to Specific Brain Region in Mice specially - hypothalmus.
The mice who lived longer and aged slowly showed increase amounts of SIRT1 in specific regions of the hypothalamus.
These mice were called BRASTO (brain-specific SIRT1-overexpressing) mice.
The BRASTO mice have a better capability to come up with energy to achieve a higher body temperature and increased activity level when food is restricted.
Same could be true for human beings but requires extensive research.
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