Saturday, December 26, 2009

Formation of memories at cellular level

Memory encoding:
When we learn new things new synapses are formed between neurons. To make it a memory these synapses has to be strengthened. This is according to a new research done by synthesizing new proteins.
Two of these proteins are: CaM Kinase and Lypla
Those proteins build the synapse and make it stronger.

Regulation of CaM Kinase and Lypla:
In normal conditions the RNA synthesizing CaM Kinase and Lypla is kept turned off by wrapping complex (proteins + micro RNA) which wraps around the RNA to do so.
When a new signal comes this wrapping complex is degraded. The RNA then becomes free and synthesizes new proteins i.e CaM Kinase and Lypla.

So degradation and synthesis of proteins go hand in hand during memory encoding. Interesting enough.

This study has been reported in Neuron journal.

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